Drug | Hemodialysis | CAPD | |

Analgesics | |||

Meperidine | Negligible | Negligible | |

Methadone | Negligible (1%) | Negligible (1%) | |

Nalmefene | Negligible (3.3%) | --- | |

Propoxyphene | Negligible | Negligible | |

Salicylates | Negligible | Negligible | |

Tilidine | Negligible (< 1%) | --- | |

Tramadol | Negligible (7%) | --- | |

Anesthetics and Drugs used during Anesthesia | |||

Gallamine | Considerable | Considerable | |

Antianxiety Agents, Sedatives and Hypnotics | |||

Buspirone | Negligible | --- | |

Chloral Hydrate | Negligible | --- | |

Ethchlorvynol | Negligible | --- | |

Glutethimide | Negligible | --- | |

Meprobamate | Negligible | --- | |

Methaqualone | Negligible | --- | |

Oxazepam | Negligible | --- | |

Phenobarbital | Negligible | --- | |

Zopiclone | Negligible | --- | |

Anticholinergics and Cholinergics | |||

Cisapride | Negligible | --- | |

Metoclopramide | Negligible | --- | |

Pirenzipine | 11-15% | --- | |

Anticoagulants, Antifibrinolytics and Antiplatelet Agents | |||

Warfarin | Negligible | Negligible | |

Low molecular weight heparins | Negligible | --- | |

Anticonvulsants | |||

Gabapentin | 50% | --- | |

Ethosuximide | 45% | --- | |

Levetiracetam | 25-50% | --- | |

Phenytoin | Negligible | Negligible | |

Primidone | 30% | --- | |

Topiramate | 50% | --- | |

Valproic Acid | Negligible (1%) | Negligible | |

Antihistamines | |||

Cetirizine | --- | Negligible (9%) | |

Cimetidine | 10-20% | Negligible (1.6%) | |

Famotidine | Negligible (6-16%) | Negligible (4.5%) | |

Fexofenadine | Negligible (< 1.7%) | --- | |

Levocabastine | Negligible (11%) | --- | |

Loratadine | Negligible | --- | |

Nizatidine | Negligible (10%) | --- | |

Ranitidine | 50-60% | Negligible (< 1%) | |

Anti-inflammatory Agents | |||

Anakinra | Negligible | Negligible | |

Azapropazone | Negligible | Negligible | |

Bromfenac | Negligible | --- | |

Leflunomide | Negligible | Negligible | |

Lornoxicam | Negligible | --- | |

Nabumetone | Negligible | --- | |

Oxaprozin | Negligible | Negligible | |

Penicillamine | 30% | --- | |

Sulindac | Negligible | --- | |

Antimicrobial Agents | |||

» Aminoglycosides | |||

Aminoglycosides | 50% | 20-50% | |

Spectinomycin | 50% | --- | |

» Carbapenems | |||

Biapenem | 90% | --- | |

Imipenem | 80-90% | Negligible | |

Meropenem | 50-70% | --- | |

» Cephalosporins | |||

Cefaclor | 33% | --- | |

Cefadroxil | 50% | --- | |

Cefamandole | 50% | Negligible (5%) | |

Cefazolin | 50% | 20% | |

Cefdinir | --- | Negligible (1.4-7.2%) | |

Cefipime | 40-70% | 26% | |

Cefixime | Negligible (1.6%) | Negligible | |

Cefmenoxime | 16-51% | Negligible (< 10%) | |

Cefmetazole | 60% | --- | |

Cefodizime | 50% | Negligible (15%) | |

Cefonicid | Negligible | Negligible (6.5%) | |

Cefoperazone | Negligible | Negligible | |

Ceforanide | 20-50% | Negligible | |

Cefotaxime | 60% | Negligible (5%) | |

Cefotetan | Negligible (5-9%) | --- | |

Defotiam | 30-40% | --- | |

Cefoxitin | 50% | Negligible | |

Cefpirome | 32-48% | Negligible (12%) | |

Cefpodoxime | 50% | --- | |

Cefprozil | 55% | --- | |

Cefroxadine | 50% | --- | |

Cefsulodin | 60% | --- | |

Ceftazidime | 50% | Negligible | |

Ceftibuten | 39% | --- | |

Ceftizoxime | 50% | Negligible (16%) | |

Ceftriaxone | 40% | Negligible (4.5%) | |

Cefuroxime | --- | 20% | |

Cephacetrile | 50% | --- | |

Cephalexin | 50-75% | 30% | |

Cephalothin | 50% | --- | |

Cephapirin | 20% | --- | |

» Macrolide Antibiotics | |||

Clindamycin | Negligible | Negligible | |

Dirithromycin | Negligible | --- | |

Lincomycin | Negligible | Negligible | |

» Monobactams | |||

Aztreoman | 40% | Negligible | |

Carumonam | 51% | --- | |

Moxalactam | 30-50% | Negligible (15-20%) | |

» Nitroimidazoles | |||

Metronidazole | 45% | Negligible (10%) | |

Ornidazole | 42% | Negligible (6%) | |

Tinidazole | 40% | --- | |

» Oxaxolindiones | |||

Linezolid | 33% | --- | |

» Penicillins | |||

Amdinocillin | 32-70% | Negligible (< 4%) | |

Amoxicillin | 30% | --- | |

Ampicillin | 40% | --- | |

Azlocillin | 30-45% | --- | |

Carbenicillin | 50% | --- | |

Cloxacillin | Negligible | --- | |

Dicloxacillin | Negligible | --- | |

Methicillin | Negligible | --- | |

Mezlocillin | 20-25% | 24% | |

Nafcillin | Negligible | --- | |

Oxacillin | Negligible | --- | |

Penicillin | 50% | --- | |

Piperacillin | 30-50% | --- | |

Temocillin | 50% | Negligible (6%) | |

Ticarcillin | 50% | Negligible | |

» Polymyxins | |||

Colistin | Negligible | Negligible | |

» Quinolones | |||

Ciprofloxacin | Negligible (2%) | Negligible (0.4-1.6%) | |

Enoxacin | Negligible | --- | |

Fleroxacin | Negligible (3-7%) | Negligible (< 10%) | |

Gatifloxacin | Negligible (14%) | Negligible (11%) | |

Levofloxacin | Negligible | Negligible | |

Lomefloxacin | Negligible | --- | |

Norfloxacin | Negligible | --- | |

Ofloxacin | Negligible (12-15%) | Negligible (4-6%) | |

Pefloxacin | --- | Negligible | |

Temafloxacin | Negligible (9.4%) | --- | |

» Streptogramins | |||

Quinupristin-dalfopristin | --- | Negligible | |

» Sulfonamides | |||

Sulfamethoxazole | 50% | Negligible (8%) | |

Trimethoprim | 50% | Negligible (7%) | |

» Tetracyclines | |||

Doxycycline | Negligible | Negligible | |

Minocycline | Negligible | Negligible | |

Vancomycin | Negligible | Negligible (15-20%) | |

Teicoplanin | Negligible | Negligible (5%) | |

» Antifungals | |||

Amphotericin B | Negligible | --- | |

Fluconazole | 40% | Negligible (18%) | |

Flucytosine | 50% | --- | |

Itraconazole | Negligible | Negligible | |

Ketoconazole | Negligible | Negligible | |

Miconazole | Negligible | Negligible | |

» Antimalarials | |||

Choloroquine | Negligible | --- | |

mefloquine | Negligible | --- | |

Quinine | Negligible | --- | |

» Antituberculous Agents | |||

Para-aminosalicylic Acid | 50% | --- | |

Ethambutol | Negligible (12%) | --- | |

Isoniazid | 75% | --- | |

» Antiviral Agents | |||

Abacavir | 24% | --- | |

Acyclovir | 60% | Negligible (< 10%) | |

Amantadine | Negligible | --- | |

Cidofovir | 50% | Negligible | |

Didanosine | 20-67% | Negligible | |

Foscarnet | 27-58% | --- | |

Ganciclovir | Negligible | --- | |

Lamivudine | Negligible | --- | |

Ribavirin | Negligible (8%) | --- | |

Vidarabine | 50% | --- | |

Zidovudine | Negligible | Negligible | |

Antineoplastics and Antimetabolites | |||

Cyclophosphamide | 30-60% | --- | |

Etoposide | Negligible | --- | |

Methotrexate | Negligible | --- | |

Paclitaxel | Negligible | --- | |

Antiulcer Agents | |||

Lansoprazole | Negligible | --- | |

Omeprazole | Negligible | --- | |

Pantoprazole | Negligible | --- | |

Rabeprazole | Negligible | --- | |

Bronchodilators | |||

Dyphylline | 28% | --- | |

Theophylline | 40% | --- | |

Zileuton | Negligible (0.5%) | --- | |

Cardiovascular Agents | |||

» Antianginal Agents | |||

Amlodipine | Negligible | Negligible | |

Bepridil | Negligible | --- | |

Diltiazem | --- | Negligible (< 0.1%) | |

Felodipine | Negligible | --- | |

Isradipine | Negligible | --- | |

Nifedipine | Negligible (< 1%) | Negligible | |

» Antiarrhythmics | |||

N-acetylprocainamide | 50% | Negligible | |

Amiodarone | Negligible | --- | |

Bretylium | Negligible | --- | |

Cibenzoline | Negligible | --- | |

Disopyramide | Negligible (2-4%) | --- | |

Flecainide | Negligible (1%) | Negligible | |

Lorcainide | Negligible (8-12%) | --- | |

Mexiletine | Negligible | Negligible | |

Procainamide | Negligible | Negligible (< 5%) | |

Propafenone | Negligible | --- | |

Quinidine | Negligible (< 1%) | --- | |

Recainam | Negligible (9%) | --- | |

Sematilide | 20-25% | --- | |

Sotalol | 40-57% | --- | |

Tocainide | 25% | Negligible (2%) | |

» Antihypertensives | |||

† Alpha_{1}-Adrenergic
Antagonists |
|||

Doxazosin | Negligible | --- | |

Urapadil | Negligible (6.5%) | --- | |

† Angiotensin Antagonists | |||

Candesartan | Negligible (0.2%) | --- | |

Erbesartan | Negligible | --- | |

Irbesartan | Negligible | --- | |

Losartan | Negligible | Negligible | |

† Beta-Adrenergic Antagonists | |||

Acebutolol | Negligible | --- | |

Atenolol | 50% | --- | |

Carvedilol | Negligible | --- | |

Esmolol | Negligible | Negligible | |

Labetalol | Negligible (2-5%) | Negligible (0.14%) | |

Metoprolol | Negligible | --- | |

Nadolol | 50% | --- | |

»
Central Acting alpha_{2}-Stimulants |
|||

Clonidine | Negligible | --- | |

Guanfacine | Negligible | --- | |

» Converting Enzyme Inhibitors | |||

Captopril | 35-40% | Negligible (< 1%) | |

Cilazapril | Negligible (14%) | --- | |

Enalapril | 50% | --- | |

Fosinopril | --- | Negligible (2%) | |

Lisinopril | 50-60% | --- | |

Omapatrilat | Negligible | --- | |

Perindopril | 55% | --- | |

Quinapril | Negligible (5.4%) | Negligible (2.6%) | |

Ramipril | Negligible | --- | |

» Vasodilators | |||

Buflomedil | Negligible (3.4-6.7%) | --- | |

Diazoxide | Negligible | --- | |

Ketansirin | Negligible | --- | |

Minoxidil | 24-43% | --- | |

Blood Lipid Lowering Agents | |||

Bezafibrate | Negligible | Negligible (1.6%) | |

Clofibrate | Negligible | --- | |

Fenofibrate | Negligible | --- | |

Gemfibrozil | Negligible | --- | |

Pravastatin | Negligible | --- | |

Cardiac Inotropes | |||

Digoxin | Negligible | Negligible (8%) | |

Fab | Negligible | Negligible | |

Hormonal Agents | |||

Epoeitin | --- | Negligible (2.3%) | |

Hypoglycemic Agents | |||

Repaglinide | Negligible | --- | |

Rosiglitazone | Negligible | --- | |

Hypourecemic Agents | |||

Allopurinol | 40% | --- | |

Psychotherapeutic Agents | |||

Citalopram | Negligible (< 1%) | --- | |

Lithium | Considerable | Considerable | |

Olanzapine | Negligible | --- | |

Sertindole | Negligible (< 0.1%) | --- | |

Sertraline | Negligible | --- | |

Tianeptine | Negligible | --- | |

Steroids | |||

Prednisone | Negligible | --- | |

Miscellaneous | |||

Cyclosporine | Negligible | --- | |

Mycophenolate | Negligible | --- | |

Sulbactam | --- | Negligible | |

Tazobactam | 30-50% | Negligible (11-13%) | |

Return to Main Index |