Primacor (Milrinone) Dosing
Loading dose: 50mcg/kg administered slowly over 10 minutes
Patient Weight (kg) Patient Weight (lbs) Loading dose (undiluted vials & cartridge units) Loading dose (diluted prefilled bag)
40 88 2.00 ml 10.00 ml
45 99 2.25 ml 11.25 ml
50 110 2.50 ml 12.50 ml
55 121 2.75 ml 13.75 ml
60 132 3.00 ml 15.00 ml
65 143 3.25 ml 16.25 ml
70 154 3.50 ml 17.50 ml
75 165 3.75 ml 18.75 ml
80 176 4.00 ml 20.00 ml
85 187 4.25 ml 21.25 ml
90 198 4.50 ml 22.50 ml
95 209 4.75 ml 23.75 ml
100 220 5.00 ml 25.00 ml
105 231 5.25 ml 26.25 ml
110 242 5.50 ml 27.50 ml
       
Maintenance dose: for concentration of 200mcg/ml (20mg/100ml bag)
       
Patient weight (kg) Patient weight (lbs) Minimum dose (ml/hr) (0.375mcg/kg/min) Standard dose (ml/hr) (0.50mcg/kg/min) Maximum dose (ml/hr) (0.75mcg/kg/min)
40 88 4.50 6.00 9.00
45 99 5.06 6.75 10.13
50 110 5.63 7.50 11.25
55 121 6.19 8.25 12.38
60 132 6.75 9.00 13.50
65 143 7.31 9.75 14.63
70 154 7.88 10.50 15.75
75 165 8.44 11.25 16.88
80 176 9.00 12.00 18.00
85 187 9.56 12.75 19.13
90 198 10.13 13.50 20.25
95 209 10.69 14.25 21.38
100 220 11.25 15.00 22.50
105 231 11.81 15.75 23.63
110 242 12.38 16.50 24.75
Dosage Adjustment in Renal Impairment
Creatinine clearance 5 ml/min 10 ml/min 20 ml/min 30 ml/min 40 ml/min 50 ml/min
Infusion rate (mcg/kg/min) 0.20 0.23 0.28 0.33 0.38 0.43
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