Dosing Equivalency Information
ACE Inhibitor Dosing Angiotensin II Receptor Blocking Agent Dosing
Drug Comparable dose based on therapeutic interchange studies, comparative clinical studies, and manufacturer's recommended dosing for hypertension Drug Comparable dose based on therapeutic interchange studies, comparative clinical studies, and manufacturer's recommended dosing for hypertension
Benazepril (Lotensin)   5mg daily 10mg daily 20 mg daily or 10mg twice daily 40mg daily or 20mg twice daily 80mg daily
Candesartan (Atacand) 4mg daily 8mg daily or 4mg twice daily 8mg daily or 4mg twice daily - 16mg daily or 8mg twice daily 32mg daily or 16mg twice daily
Captopril (Capoten)     25mg twice daily or three times daily 50mg twice daily 100mg twice daily 200mg twice daily
Enalapril (Vasotec) 2.5mg daily 5mg daily 10mg daily or 5mg twice daily 20mg daily or 10mg twice daily 40mg daily or 20mg twice daily   Eprosartan (Teveten) 400mg daily 600mg daily 800mg daily or 400mg twice daily  
Fosinopril (Monopril)     10mg daily or 5mg twice daily 20mg daily or 10mg twice daily 40mg daily or 20mg twice daily 80mg daily or 40mg twice daily Irbesartan (Avapro) 75mg daily 150mg daily 300mg daily  
Losartan (Cozaar) 25mg daily 50mg daily or 25mg twice daily 100mg daily or 50mg twice daily  
Lisinopril (Prinivil, Zestril)   5mg daily 10mg daily or 5mg twice daily 20mg daily or 10mg twice daily 40mg daily or 20mg twice daily 80mg daily or 40mg twice daily
Olmesartan (Benicar) 5mg daily 10mg daily 20mg daily 40mg daily
Moexipril (Univasc)   3.75mg daily 7.5mg daily or 3.75mg twice daily 15mg daily or 7.5mg twice daily 30mg daily or 15mg twice daily 60mg daily or 30mg twice daily
Telmisartan (Micardis)   20mg daily 40mg daily 80mg daily
Perindopril (Aceon)   2mg daily 4mg daily or 2mg twice daily 8mg daily or 4mg twice daily 16mg daily or 8mg twice daily   Valsartan (Diovan) 40mg daily or 20mg twice daily 80mg daily or 40mg twice daily 160mg daily 320mg daily
Quinapril (Accupril)   5mg daily 10mg daily or 20mg daily 20mg daily or 10mg twice daily 40mg daily or 20mg twice daily 80mg daily or 40mg twice daily
Ramipril (Altace)   1.25mg daily 2.5mg daily or 1.25mg twice daily 5mg daily or 2.5mg twice daily 10mg daily or 5mg twice daily 20mg daily or 10mg twice daily Proton Pump Inhibitor Dosing
Drug Usual Dosage H. Pylori Dosing
Esomeprazole (Nexium) 40mg daily 40mg daily
Trandolapril (Mavik)   0.5mg daily 1mg daily 2mg daily 4mg daily 4mg twice daily
Lansoprazole (Prevacid) 30mg daily 30mg twice daily
Omeprazole (Prilosec) 20mg daily 20-40mg daily
HMG-CoA Reductase Inhibitor Dosing Pantoprazole (Protonix) 40mg daily 40mg IV twice daily
Drug Daily adult dose providing similar average LDL lowering (by percentage)
Atorvastatin (Lipitor)     10mg (35-39%) 20mg (43%) 40mg (50%) 80mg (60%) Rabeprazole (Aciphex) 20mg daily 20mg twice daily
Fluvastatin (Lescol, Lescol XL) 20mg (22%) 40mg (25%) 80mg (35% as XL)      
Lovastatin (Mevacor) 10mg (21%) 20mg (24-27%) 40mg (30-31%) to 80mg (40-42%) as 40mg twice daily 80mg (40-42%) as 40mg twice daily    
H2 Antagonist Dosing
Drug Dosing
Cimetidine (Tagamet) 400mg daily 800mg daily
Pravastatin (Pravachol) 10mg (22%) 20mg (32%) 40mg (34%) to 80mg (37%) 80mg (37%)    
Famotidine (Pepcid) 20mg daily 40mg daily
Rosuvastatin (Crestor)       5mg (45%) 10mg (46-52%) to 20mg (47-55%) 20mg (47-55%) to 40mg (55-63%) Nizatidine (Axid) 150mg daily 300mg daily
Ranitidine (Zantac) 150mg daily 300mg daily
Simvastatin (Zocor) 5mg (26%) 5mg (26%) to 10mg (30%) 20mg (38%) 40mg (29-41%) 80mg (36-47%)  
Simvastatin/Ezetimibe (Vytorin)       10/10mg (45%) 10/20mg (52%) to 10/40mg (55%) 10/40mg (55%) to 10/80mg (60%)
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Comparison of LDL lowering
Zocor dosing restrictions
Coreg/Coreg CR Dosing Hytrin to Cardura Conversion
Coreg Dose Coreg CR Dose Cardura dose = Hytrin dose x 0.8 (rounded to nearest whole number)
3.125mg twice daily 10mg daily
6.25mg twice daily 20mg daily Conversion of IV Cardizem to oral Cardizem
Oral dose (mg/day) is approximately equal to [rate (mg/hr) X 3 + 3] X 10
12.5mg twice daily 40mg daily
25mg twice daily 80mg daily